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Medchemexpress LLC FzM1 100mg | 1680196-54-6 | 100 MG
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Supplier:  Medchemexpress LLC HY116553100MG

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FzM1 is a small-molecule negative allosteric modulator (NAM) of the Frizzled receptor FZD4 that reduces WNT5A-dependent WNT responsive element (WRE) activity and inhibits WNT/β-catenin signaling. It binds an allosteric site in intracellular loop 3 (ICL3) of FZD4 and is supplied as a solid research reagent.

  • Negative allosteric modulator of the FZD4 receptor.
  • Reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh ≈ -6.2).
  • Molecular formula C21H16N2O2S; molecular weight 360.43.
  • Purity approximately 98.7% as supplied.
  • Storage: powder at -20°C; in solvent -80°C up to 6 months or -20°C up to 1 month.

Catalog No. 50-002-26204


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