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Medchemexpress LLC FzM1.8 | 322.3 g/mol | C18H14N2O4 | 10MG
Supplier: Medchemexpress LLC HY11716310MG
FzM1 8 derives from FzM1 is an allosteric agonist of FZD4 with pEC50 of 6 4 FzM1 8 binds to FZD4 and activates the WNT/ -catenin pathway by promoting TCF/LEF transcriptional activity in the absence of any WNT ligand FzM1 8 stabilizes FZD4 with an increased affinity for heterotrimeric G protein and stimulates the release of the G subunit that in turn activates PI3K[1]
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