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Sigma Aldrich Fine Chemicals Biosciences G 418 Solution
Supplier: Sigma Aldrich Fine Chemicals Biosciences G418RO
O-2-Amino-2 7-dideoxy-delta-glycero-alpha-delta-glucoheptopyranosyl[1-4]-O-3-deoxy-4C-methyl-3-[methyl-amino]-beta-L-arabinopyranosyl-delta-streptamine disulfate salt G-418 an aminoglycoside antibiotic is used as a dominant selection agent in transfection experiments. The antibiotic interferes with the function of 80S ribosomes and blocks protein synthesis in eukaryotic cells. Transfection of neomycin-resistance genes into cells results in resistance to G-418 and enables the cells to grow in culture media containing G-418.
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