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Apexbio Technology LLC G150 2369751-30-2 10mg
Supplier: Apexbio Technology LLC B877710
G150 (CAS 2369751-30-2) is a selective inhibitor of human cyclic GMP-AMP synthase (h-cGAS) an enzyme crucial for recognizing double-stranded DNA (dsDNA) By specifically blocking h-cGAS enzymatic activity G150 suppresses dsDNA-induced synthesis of the secondary messenger 2 3 -cyclic GMP-AMP (cGAMP) consequently decreasing expression of type I interferons In cellular assays G150 inhibits h-cGAS activity with an IC50 of 10 2 nM This compound serves as a useful tool in studying the h-cGAS-STING signaling axis in inflammation immune regulation and associated diseases
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