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Cayman Chemical GadoterIdol 100mg

Supplier: Cayman Chemical 33577100 MG

A histamine H3 receptor agonist (KI 0.4 nM in SK-N-MC cell membranes expressing the human receptor) selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors respectively (Kis 16 M for both) but also agonizes H4 receptors (KI 9 nM in SK-N-MC cell membranes expressing the human receptor) decreases hypothalamic histamine release in anesthetized rats at 5 mg/kg decreases flinching in the formalin test in rats at 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg
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