Medchemexpress LLC GAK inhibitor 49 | 319492-82-5 | MFCD29701419 | 98.8% | 370.40 | C20H22N2O5 | 10MM 1ML

Supplier:  Medchemexpress LLC HY12479310MM 1ML

GAK inhibitor 49 is a selective, ATP-competitive inhibitor of Cyclin G-associated kinase (GAK) that demonstrates sub-nanomolar binding potency (Ki = 0.54 nM) and cellular activity (cell IC50 = 56 nM). It is provided as a solid and as a 10 mM solution in DMSO, with a reported purity of 98.79%. The compound has good solubility in DMSO and documented storage recommendations for powders and stock solutions to preserve activity.

• Selective ATP-competitive inhibitor of Cyclin G-associated kinase (GAK).
• Sub-nanomolar binding potency (Ki = 0.54 nM).
• Cellular activity at low nanomolar concentrations (cell IC50 = 56 nM).
• Supplied as solid and as a 10 mM solution in DMSO.
• High reported purity: 98.79%.
• DMSO solubility suitable for in vitro use (62.5 mg/mL).
• Recommended storage and aliquoting to minimize freeze-thaw and preserve stability.

Catalog No. 50-002-36732