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TARGETMOL CHEMICALS INC GALETERONE 25MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T650925MG

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Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Galeterone (VN 124) is an orally bioavailable small-molecule androgen receptor modulator and CYP17 lyase inhibitor with potential antiandrogen activity. Galeterone exhibits three distinct mechanisms of action 1) as an androgen receptor antagonist 2) as a CYP17 lyase inhibitor and 3) by decreasing overall androgen receptor levels in prostate cancer tumors all of which may result in a decrease in androgen-dependent growth signaling. Localized to the endoplasmic reticulum (ER) the cytochrome P450 enzyme CYP17 (P450C17 or CYP17A1) exhibits both 17alpha-hydroxylase and 17 20-lyase activities and plays a key role in the steroidogenic pathway that produces progestins mineralocorticoids glucocorticoids androgens and estrogens. purity: 99%

Catalog No. 50-257-9343


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