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Medchemexpress LLC Galicaftor | 1918143-53-9 | 98.56% | 559.46 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11111150MG

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Galicaftor is a potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It can be used for cystic fibrosis research. In vitro, Galicaftor exhibits potent functional activity in primary patient cells harboring F508del/F508del CFTR, with an EC50 <10 nM. In rats, pharmacokinetic tests showed a T1/2 of 2.7 hours (i.v.) and bioavailability (%F) of 74% for intragastric administration.

  • Potent and orally active cystic fibrosis transmembrane conductance regulator corrector
  • Useful for cystic fibrosis research

Catalog No. 50-003-43190


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