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Medchemexpress LLC Ganoderic acid D | 108340-60-9 | 514.65 | 1 ML
Supplier: Medchemexpress LLC HYN151110MM/1ML
Ganoderic acid D is a highly oxygenated tetracyclic triterpenoid and a major active component of *Ganoderma lucidum*. It upregulates SIRT3 protein expression, inducing deacetylated cyclophilin D (CypD) by SIRT3. This compound inhibits energy reprogramming in colon cancer cells, including glucose uptake, lactate production, pyruvate, and acetyl-coenzyme production. Ganoderic acid D also induces apoptosis in HeLa human cervical carcinoma cells and inhibits the growth of numerous cancer cell lines.
- Upregulates SIRT3 protein expression and induces deacetylated cyclophilin D (CypD).
- Inhibits energy reprogramming in colon cancer cells.
- Induces apoptosis in human cervical carcinoma cells.
- Inhibits the growth of various cancer cell lines.
- Exhibits anti-inflammatory activity.
- Induces G2/M phase arrest.
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