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Cayman Chemical Garenoxacn 5mg

Supplier: Cayman Chemical 335995 MG
A quinolone antibiotic; active against a variety of Gram-positive and Gram-negative bacteria (MIC90s = 0.025-6.25 and 0.0125-100 UG/ml, respectively); inhibits E. coli DNA gyrase supercoiling and S. aureus topoisomerase IV decatenation activities (IC50s = 0.17 and 2.19 mg/L, respectively); selective for S. aureus topoisomerase IV over human topoisomerase II (IC50 = 509.7 UG/L); efficacious against systemic quinolone-resistant S. aureus infection and pneumonia induced by the penicillin-resistant S. pneumoniae clinical isolate D-979 in mice (ED50s = 0.0189 and 0.0278 mg/animal, respectively)
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