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Apexbio Technology LLC Gatifloxacin hydrochloride 121577-32-0 5g
Supplier: Apexbio Technology LLC B12155000
Gatifloxacin hydrochloride (121577-32-0) is a small-molecule inhibitor targeting bacterial DNA gyrase and topoisomerase IV It is designed to inhibit these enzymes thereby interfering with bacterial DNA replication and transcription Gatifloxacin hydrochloride exerts its biological activity primarily through inhibition of bacterial DNA gyrase and topoisomerase IV In in vitro studies Gatifloxacin hydrochloride demonstrates inhibitory activity with an IC50 value of 13 8 g/ml for Staphylococcus aureus topoisomerase IV and 0 109 g/ml for Escherichia coli DNA helicase Based on these pharmacological properties Gatifloxacin hydrochloride holds research potential in antimicrobial efficacy assays microbial resistance studies and mechanistic investigations of DNA enzyme inhibition
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