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Medchemexpress LLC GBT1118 | 1628799-51-8 | C19H20N2O4 | 50 MG
Supplier: Medchemexpress LLC HY15318250MG
GBT1118 is a potent and orally active allosteric modifier of hemoglobin oxygen affinity, enhancing tolerance to severe hypoxia. It works by covalently and reversibly binding to the N-terminal valine of the hemoglobin α chain, allosterically increasing intracellular hemoglobin's affinity for oxygen. This action helps protect red blood cells from damage during severe hypoxia.
- Potent and orally active allosteric modifier of hemoglobin oxygen affinity
- Increases tolerance to severe hypoxia
- Binds covalently and reversibly to the hemoglobin α chain
- Increases intracellular hemoglobin affinity for oxygen
- Protects red blood cells from damage during severe hypoxia
- Improved oxygen delivery during hypoxia in animal studies
- Increased blood oxygen loading in the lungs in animal studies
- Decreased hypoxia in vital tissues and lowered lactate levels in animal studies
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