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Medchemexpress LLC GDC-0152 | 873652-48-3 | 99.7% | 498.64 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY13638100MG

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GDC-0152 is a potent inhibitor of IAPs (Inhibitor of Apoptosis Proteins) that binds to the BIR3 domains of XIAP, cIAP1, cIAP2, and the BIR domain of ML-IAP. It activates caspases 3 and 7 and induces rapid degradation of cIAP1, making it suitable for apoptosis research.

  • Binds to BIR3 domains of XIAP, cIAP1, cIAP2
  • Binds to BIR domain of ML-IAP
  • Activates caspases 3 and 7 in a dose- and time-dependent manner
  • Induces rapid degradation of cIAP1
  • Has moderate predicted hepatic clearance and plasma-protein binding
  • For research use only

Catalog No. 50-003-48989


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