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Medchemexpress LLC GDF-15 Mouse HEK29 100ug | 100ug
Supplier: Medchemexpress LLC HYP77945A100UG
Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor (TGF- ) superfamily GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1) placental transforming growth factor- (PTGFB) prostate-derived factor (PDF) and placental bone morphogenetic protein (PLAB) GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging cancer and metabolic processes GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET AKT ERK1/2 and phospholipase C (PLC )[1] GDF-15 Protein Mouse (HEK293 hFc) has 115 amino acids expressed by HEK293 cells with N-terminal hFc tag
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