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Medchemexpress LLC GDP366 | 501698-03-9 | 375.45 | 50 MG

Supplier: Medchemexpress LLC HYU0017750MG
GDP366 is a dual inhibitor of survivin and Op18. It induces cell growth inhibition, cellular senescence, and mitotic catastrophe in human cancer cells.
- Potently and selectively inhibits the expression of survivin and Op18
- Decreases mRNA and protein levels of survivin and Op18
- Inhibitory effect is independent of p53 and p21 status
- Significantly inhibits tumor cell growth in vitro and in vivo
- Induces polyploidy in multiple cancer cell lines
- Increases chromosomal instability
- Induces cellular senescence by inhibiting telomerase activity
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