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Medchemexpress LLC GDP366 | 501698-03-9 | 375.45 | 50 MG
SDP

Supplier:  Medchemexpress LLC HYU0017750MG

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GDP366 is a dual inhibitor of survivin and Op18. It induces cell growth inhibition, cellular senescence, and mitotic catastrophe in human cancer cells.

  • Potently and selectively inhibits the expression of survivin and Op18
  • Decreases mRNA and protein levels of survivin and Op18
  • Inhibitory effect is independent of p53 and p21 status
  • Significantly inhibits tumor cell growth in vitro and in vivo
  • Induces polyploidy in multiple cancer cell lines
  • Increases chromosomal instability
  • Induces cellular senescence by inhibiting telomerase activity

Catalog No. 50-004-49683


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