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Medchemexpress LLC Gelsemine | 509-15-9 | 322.40 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN0388
Gelsemine is an alkaloid derived from the Chinese herb *Gelsemium elegans*. It has been shown to be effective in mitigating chronic pain and exhibits antinociceptive effects. This compound is an effective agent for the treatment of both neuropathic pain and sleep disturbance in partial sciatic nerve ligation (PSNL) mice. It has demonstrated analgesic effects on PSNL-induced mechanical allodynia and thermal hyperalgesia, increasing mechanical threshold and prolonging thermal latencies.
- Alkaloid sourced from *Gelsemium elegans*.
- Mitigates chronic pain.
- Exhibits antinociceptive effects.
- Treats neuropathic pain.
- Treats sleep disturbance (in PSNL mice).
- Increases non-rapid eye movement (NREM) sleep.
- Decreases wakefulness.
- Decreases c-Fos expression.
- For research use only.
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