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Apexbio Technology LLC Gemcitabine HCl 122111-03-9 10mM (in 1mL H2O)
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Supplier:  Apexbio Technology LLC A14025.1

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Gemcitabine HCl (CAS 122111-03-9) is a small molecule inhibitor of DNA synthesis commonly employed in biomedical research targeting cancer cell proliferation It acts by impeding DNA replication exerting cytotoxic effects in various cancer cell models When evaluated in vitro IC50 values have been reported as 240 4 29 0 M (CCRF-CEM/dCK/) 14 7 2 8 M (TC-1) 36 7 5 1 M (TC-1-GR) 50 nM (PANC 1) and 49 7 17 7 nM (MIA PACA-2) Additionally preclinical studies have demonstrated enhanced apoptosis and growth inhibition in pancreatic cancer models (COLO 357 L3 6pl) highlighting Gemcitabine HCl s significance as a valuable research tool for investigating tumor biology and therapeutic interventions

Catalog No. 50-000-63215


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