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Medchemexpress LLC Geneticin disulphate | 50 ML
Supplier: Medchemexpress LLC HYK105650ML
MCE G418 Selective Antibiotic, Sterile (50 mg/mL) is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It functions by binding to the 80S subunit of the bacterial ribosome, thereby inhibiting protein synthesis in both prokaryotic and eukaryotic cells. Resistance to G418 selective antibiotic is conferred by the E. coli APH (3) I and APH (3) II resistance genes. The gene becomes APH (3) II on Tn5 and APH (3) I on Tn601. Consequently, G-418 selective antibiotic can be utilized to select and maintain prokaryotic or eukaryotic cells that carry the G418 resistance gene.
- Aminoglycoside antibiotic.
- Produced by Micromonospora rhodorangea.
- Inhibits protein synthesis in both prokaryotic and eukaryotic cells.
- Binds to the 80S subunit of the bacterial ribosome.
- Can be used to select and maintain prokaryotic or eukaryotic cells carrying the G418 resistance gene.
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