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Apexbio Technology LLC GI-530159 69563-88-8 200mg
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Supplier:  Apexbio Technology LLC C6889200

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GI-530159 (CAS 69563-88-8) is a small molecule activator selective for the TREK1 and TREK2 two-pore domain potassium channels exhibiting greater specificity for TREK1/2 over other related channels such as TRAAK and TASK3 It has been shown to potentiate TREK1 channel activity with an EC50 of 0 76 M In experimental models GI-530159 reduces excitability in rat dorsal root ganglion neurons indicating its capability to modulate neuronal activity These properties highlight its utility as a pharmacological tool in studies related to neuronal excitability pain pathways and the pathophysiology of neurological disorders involving potassium channel dysfunction

Catalog No. 50-000-90417


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