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TARGETMOL CHEMICALS INC GI254023X 5MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T75225MG

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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s 2.5 and 5.3 nM) with 100-fold selectivity for the (alpha)-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation. purity: 98%

Catalog No. 50-257-9185


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