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Cayman Chemical GIlterItInIb 5mg
Supplier: Cayman Chemical 215035 MG
A FLT3 inhibitor (IC50 = 5 nM for the wild-type enzyme); inhibits various FLT3 mutants (IC50s = 1.4-12.2 nM); also inhibits Axl and c-Kit (IC50s = 41 and 102 nM, respectively); decreases the viability of blast cells isolated from patients with relapsed AML in a concentration-dependent manner
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