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Medchemexpress LLC Glpg1837 (abbv-974) | 1654725-02-6 | 99.9% | 348.42 | 10 UG
Supplier: Medchemexpress LLC HY11109910MG
GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. It increases the conductivity of the G551D CFTR channel with an obtained potency of 181 nM.
- Potent and reversible CFTR potentiator.
- EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
- Increases the conductivity of the G551D CFTR channel with an obtained potency of 181 nM.
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