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Creative Biomart Teduglutide; GLP-2
Supplier: Creative Biomart THP0025
The product is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. The product differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that the product is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4.
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