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Sigma Aldrich Fine Chemicals Biosciences Glucose Uptake Fluorometri
Supplier: Sigma Aldrich Fine Chemicals Biosciences MAK0841KT
Glucose is the primary source of energy for most cells.Transport of glucose across the plasma membrane is the first rate limiting step in glucose metabolism. Glucose uptake is facilitated by the GLUT family of transporter proteins whose expression and activity are regulated by multiple mechanisms. Glucose uptake is upregulated in many cancer cells which exhibit high rates of aerobic glycolysis. Cells exhibiting insulin resistance show diminished glucose uptake in response to insulin stimulation.
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