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Medchemexpress LLC Glycochenodeoxycholic acid | 640-79-9 | 1 ML
Supplier: Medchemexpress LLC HYN233410MM/1ML
Glycochenodeoxycholic acid is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. It inhibits autophagosome formation, impairs lysosomal function, and induces stemness and chemoresistance in hepatocellular carcinoma cells (HCC) by activating the STAT3 signaling pathway. This compound is considered promising for research in fields such as cholestasis disease, HCC, and primary sclerosing cholangitis (PSC).
- Inhibits autophagosome formation
- Impairs lysosomal function
- Increases lysosomal pH in human normal liver cells
- Induces stemness and chemoresistance in HCC
- Activates the STAT3 signaling pathway
- Useful for research into cholestasis disease, hepatocellular carcinoma, and primary sclerosing cholangitis
- For research use only
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