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Medchemexpress LLC Glycoursodeoxycholic acid | 64480-66-6 | 449.62 | 5 MG
Supplier: Medchemexpress LLC HYN14245MG
Glycoursodeoxycholic acid, also known as GUDCA, is an acyl glycine and a bile acid-glycine conjugate. It is a metabolite of ursodeoxycholic acid and is intended for research use only. This antioxidant compound has shown therapeutic efficacy in neurodegenerative models and diseases by preventing oxidative stress, metabolic alterations, and cell demise.
- Fully abrogates unconjugated bilirubin (UCB)-induced cytochrome c oxidase inhibition.
- Significantly prevents oxidative stress, metabolic alterations, and cell demise.
- Reduces cytosolic SOD1 inclusions, decreasing mitochondria viability, caspase-9 activation, and apoptosis.
- Demonstrates preventive and restorative effects against UCB-induced blood-brain barrier disruption and damage to human brain microvascular endothelial cells.
- Used for research purposes.
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