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Medchemexpress LLC GN44028 | 1421448-26-1 | 99.6% | 305.33 | 100 MG
Supplier: Medchemexpress LLC HY1102661MG
GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1α inhibitor, with an IC50 of 14 nM. It inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. It can be used in the research of cancers.
- Potent and orally active HIF-1α inhibitor
- IC50 of 14 nM against HIF-1α
- Specifically inhibits hypoxia-induced HIF-1α transcriptional activity
- Does not suppress HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization
- Useful in cancer research
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