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Medchemexpress LLC GNE-0946 | 1677667-24-1 | 98.1% | 460.79 | 25 MG
Supplier: Medchemexpress LLC 25MGHY19774
GNE-0946 is described as a potent and selective RORγ (RORc) agonist with an EC50 value of 4 nM for HEK-293 cells. It is intended for research use only and not for sale to patients.
- Potent and selective RORγ (RORc) agonist.
- EC50 value of 4 nM for HEK-293 cell.
- Exhibits inverse agonist activity at GAL4-fused human RORc, RORa, and RORb in HEK293T cells.
- Shows antiinflammatory activity in human PBMC, inhibiting IL-17 production.
- Available in solid and solution forms.
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