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Cayman Chemical GnglIosID GM2bovIn braIn 500ug
Supplier: Cayman Chemical 27192500 UG
A mixture of ganglioside GM2 with C18:1 and C20:1 sphingoid backbones; induces activated T cell death at 150 μg/ml in vitro; serum levels are increased in patients with breast cancer or cholangiocarcinoma; levels are elevated in the brain of patients with Sandhoff disease; accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2
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