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Apexbio Technology LLC Gossypol 303-45-7 200mg
Supplier: Apexbio Technology LLC N2135200
Gossypol (CAS 303-45-7) is a naturally occurring polyphenolic compound isolated from cotton plant tissues It is known to disrupt reproductive and immune functions through various biochemical pathways Mechanistically gossypol inhibits cAMP formation and progesterone secretion in bovine granulosa cells impairs sperm motility and hampers embryonic development in vitro in a dose-dependent manner In murine lymphocytes it suppresses proliferation and induces apoptosis of T and B cell subsets In vivo studies in rodents indicate hepatotoxicity and alterations in hepatic enzyme activity at certain dosages Gossypol is widely used in biomedical research to study cell signaling reproductive biology and immune modulation
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