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Cayman Chemical GPX4 InhIbItr 17 1mg

Supplier: Cayman Chemical 420061 MG
A GPX4 inhibitor and ferroptosis inducer; inhibits GPX4 activity by 49.16% at 1 µM; increases the production of ROS and levels of MDA in OS-RC-2 cells 0.5 µM; induces ferroptosis in HT-1080 cells (IC50s = 0.007 and 1.486 µM, in the absence and presence of ferrostatin-1, respectively); reduces tumor volume and intratumoral GPX4 levels in an OS-RC-2 mouse xenograft model 20 mg/kg
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