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Apexbio Technology LLC Granisetron HCl 107007-99-8 50mg
Supplier: Apexbio Technology LLC A129550
Granisetron HCl (CAS 107007-99-8) is a selective antagonist of the serotonin 5-hydroxytryptamine type 3 (5-HT sub 3 /sub ) receptor By competitively inhibiting 5-HT sub 3 /sub receptor-mediated signaling Granisetron HCl suppresses serotonin-induced activation of the vomiting reflex pathway in both central and peripheral nervous systems This pharmacological activity underlies its utility in preventing and investigating the mechanisms of chemotherapy-induced and postoperative nausea and vomiting Granisetron HCl is widely employed in preclinical and clinical studies to elucidate 5-HT sub 3 /sub receptor function and to explore antiemetic strategies
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