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Medchemexpress LLC Griseofulvin | 126-07-8 | 98.9% | 352.77 | 10 G
Supplier: Medchemexpress LLC HY1758310G
Griseofulvin is an orally active antifungal antibiotic with antitumor activity. It induces apoptosis and G2/M cell cycle arrest in cancer cells. It also exhibits cardiovascular modulatory activity, reducing angina pectoris and relieving hand artery spasm associated with onychomycosis and peripheral vascular diseases like shoulder-hand syndrome.
- Orally active antifungal antibiotic
- Antitumor activity
- Induces apoptosis and G2/M cell cycle arrest in cancer cells
- Cardiovascular modulatory activity
- Reduces angina pectoris and relieves hand artery spasm
- Inhibits growth of various cell lines
- Increases ventricular contractility and coronary blood flow in animals
- Reduces tumor volume in xenograft mice
- Microbial metabolite
- Microtubule/Tubulin inhibitor
- Wee1, Caspase, and Bcl-2 Family inhibitor
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