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Apexbio Technology LLC GS-9620 1228585-88-3 10mg
Supplier: Apexbio Technology LLC A344410
GS-9620 (CAS 1228585-88-3) is an orally active small-molecule agonist targeting Toll-like receptor 7 (TLR7) It is designed to activate TLR7 signaling thereby inducing innate antiviral responses GS-9620 exerts its biological activity primarily through TLR7 activation in endolysosomal compartments of plasmacytoid dendritic cells (pDCs) and B cells leading to the production of type I interferons (e g IFN- ) In cell-based studies GS-9620 demonstrates selectivity for TLR7 activation with an EC value of 291 nM Based on these pharmacological properties GS-9620 holds research potential in studies of antiviral immune mechanisms particularly in hepatitis B virus suppression and immune modulation pathways
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