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Medchemexpress LLC GSK-3β inhibitor 13 | 2227316-74-5 | 99.74% | 414.46 | 5 MG
Supplier: Medchemexpress LLC HY1490545MG
GSK-3β inhibitor 13 is an orally active and potent GSK-3β inhibitor with blood-brain permeability. It significantly decreases the phosphorylation of tau, which is associated with the formation of neurofibrillary tangles in Alzheimer's disease.
- Orally active and potent GSK-3β inhibitor
- Exhibits blood-brain permeability
- Inhibits GSK-3β with an IC50 of 0.73 nM
- Inhibits GSK-3α with an IC50 of 0.35 nM
- Decreases phosphorylation of tau (IC50=58 nM)
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