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Medchemexpress LLC GSK 3008348 hydrochloride | 1629249-40-6 | 99.86% | 524.11 | 100 MG
Supplier: Medchemexpress LLC HY19767A100MG
GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6 with varying IC50 values for αvβ6, αvβ1, αvβ3, αvβ5, and αvβ8. It targets the αvβ6 integrin, inhibiting TGF-β activation and thereby alleviating the fibrotic process. Additionally, it prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor on host cells, which inhibits viral entry. This compound is suitable for research on pulmonary fibrosis and different types of cancer.
- Antagonist of integrin αvβ6 with high affinity.
- Inhibits TGF-β activation.
- Alleviates the fibrotic process.
- Prevents FMDV binding to αvβ6 integrin, inhibiting viral entry.
- Useful for research on pulmonary fibrosis and various cancers.
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