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Medchemexpress LLC GSK 3008348 hydrochloride | 1629249-40-6 | 99.9% | 524.11 | 50 MG
Supplier: Medchemexpress LLC HY19767A50MG
GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6. It targets the αvβ6 integrin, inhibits TGF-β activation, and can alleviate the fibrotic process. It also prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor, inhibiting virus entry. GSK 3008348 hydrochloride can be used for research on pulmonary fibrosis and various types of cancer.
- Small molecule antagonist of integrin αvβ6.
- Inhibits TGF-β activation.
- Alleviates the fibrotic process.
- Prevents binding of foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor.
- Inhibits viral entry.
- Used for research on pulmonary fibrosis and various types of cancer.
- Antagonizes integrin αvβ6 with high affinity.
- Suppresses FMDV RNA replication and virus production.
- Decreases TGF-β1-activated procollagen I production.
- Inhibits TGF-β-induced phosphorylation of ERK1/2 and STAT3.
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