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Medchemexpress LLC GSK-872 | 1346546-69-7 | MFCD30481302 | 99.8% | 383.49 g/mol | C19H17N3O2S2 | 25 MG
Supplier: Medchemexpress LLC HY10187225MG
GSK-872 is a potent, selective small-molecule inhibitor of receptor-interacting protein kinase 3 (RIPK3) used in research to probe necroptosis and RIPK3-dependent signaling. It binds the RIP3 kinase domain at low nanomolar concentrations and is supplied as a solid powder for laboratory use.
- Binds RIP3 kinase domain with IC50 approximately 1.8 nM and inhibits kinase activity (IC50 approximately 1.3 nM).
- High biochemical selectivity for RIPK3 versus other kinases.
- Useful tool compound for necroptosis and cell-death pathway studies.
- Provided as a powder suitable for preparing stock solutions in common solvents.
- Molecular formula C19H17N3O2S2 and molecular weight 383.49 g/mol.
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