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Apexbio Technology LLC GSK J2 1394854-52-4 50mg
Supplier: Apexbio Technology LLC B568550
GSK J2 is an inactive stereoisomer compound used as an experimental negative control for the histone demethylases JMJD3 (KDM6B) and UTX (KDM6A) GSK J2 does not inhibit the enzymatic activity of JMJD3 and UTX JMJD3 and UTX catalyze demethylation of histone H3 lysine 27 trimethyl (H3K27me3) and dimethyl (H3K27me2) influencing chromatin structure and gene expression GSK J2 is applied in biological research to confirm target specificity and distinguish off-target effects related to JMJD3/UTX inhibition by GSK-J1
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