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Medchemexpress LLC GSK1034702 25mg | 932373-87-0 | 25MG
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Supplier:  Medchemexpress LLC HY10711125MG

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GSK1034702 is an orally active and allosteric agonist of M1 mAChR (pEC50 8 1) that can cross the blood-brain barrier GSK1034702 activates the Gq/11 protein-mediated signaling pathway enhancing neuronal firing and long-term potentiation (LTP) in the CA1 region of the hippocampus GSK1034702 can modulate hippocampal function improve memory encoding in the nicotine withdrawal cognitive dysfunction model and show pro-cognitive effects in rodents GSK1034702 can be used for the study of the mechanisms of cognitive impairment diseases such as Alzheimer s disease and has certain peripheral M receptor activation-related side effects (such as gastrointestinal reactions)[1 [2

Catalog No. 50-002-40377


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