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Medchemexpress LLC Gsk1324726a | 1300031-52-0 | 99.9% | 434.91 | 100 MG
Supplier: Medchemexpress LLC HY13960100MG
GSK1324726A, also known as I-BET726, is a novel, potent, and selective inhibitor of BET proteins. It demonstrates high affinity for BRD2, BRD3, and BRD4, and has shown significant inhibition of neuroblastoma tumor growth both in vitro and in vivo.
- Potent and selective inhibitor of BET proteins
- High affinity for BRD2 (IC50=41 nM), BRD3 (IC50=31 nM), and BRD4 (IC50=22 nM)
- Causes potent growth inhibition and cytotoxicity in neuroblastoma cell lines
- Inhibits neuroblastoma tumor growth in models
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