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Medchemexpress LLC GSK2018682 | 1034688-30-6 | 98.02% | 440.88 | 1 ML
Supplier: Medchemexpress LLC HY1951110MM/1ML
GSK2018682 is an agonist for S1P1 and S1P5 receptors with pEC50s of 7.7 and 7.2, respectively, and exhibits no agonist activity towards human S1P2, S1P3, or S1P4. It is used in the research of multiple sclerosis. The appearance of GSK2018682 is a white to off-white solid. It is for research use only and not sold to patients. The compound has a molecular formula of C22H21ClN4O4. GSK2018682 can be dissolved in DMSO at a concentration of ≥ 125 mg/mL (283.52 mM) for in vitro use. For in vivo applications, various dissolution protocols are available using co-solvents like DMSO, PEG300, Tween-80, Saline, or Corn Oil. Stock solutions can be stored at -80°C for 2 years or -20°C for 1 year.
- Specific agonist activity for S1P1 and S1P5 receptors.
- Useful in multiple sclerosis research.
- Functions as a selective research tool for these targets and disease.
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