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Medchemexpress LLC GSK2606414 | 1337531-36-8 | 99.9% | 451.44 | 250 MG
Supplier: Medchemexpress LLC 250MGHY18072
GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM. It inhibits PERK activation in cells and has been shown to inhibit the growth of a human tumor xenograft in mice.
- Cell-permeable
- Orally available
- Potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK)
- Inhibits PERK activation in cells
- Inhibits the growth of a human tumor xenograft in mice
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