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Medchemexpress LLC GSK481 | 1622849-58-4 | 98.0% | 377.39 | C21H19N3O4 | 50 MG
Supplier: Medchemexpress LLC HY10013150MG
GSK481 is a potent, selective inhibitor of receptor-interacting protein 1 (RIP1) kinase for biochemical and cellular research. It inhibits RIP1 autophosphorylation (Ser166) with low-nanomolar potency and shows cellular activity in U937 assays. Documented physicochemical properties, solubility data, and storage recommendations support its use in both in vitro and in vivo experiments.
- Potent RIP1 kinase inhibition with low-nanomolar biochemical activity.
- Demonstrated cellular activity in immune-relevant cell assays.
- Useful for studies of necroptosis and RIPK1-mediated signaling.
- Documented solubility in DMSO and multiple in vivo vehicle systems.
- Long-term powder stability with recommended storage conditions.
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