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Cayman Chemical GSK484 (hydrochloride), 1652591-81-5, 5 mg
Supplier: Cayman Chemical 174885
Molecular Formula C27H31N5O3 • HCl, Purity ≥95%, Formula Weight 510.0; A reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme; blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of NETs in both mouse and human neutrophils.
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