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Medchemexpress LLC GSK591 (EPZ015866) | 1616391-87-7 | ≥95.0% | 380.48 g/mol | C22H28N4O2 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1002351MG

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GSK591 (EPZ015866) is a selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) used as a research chemical probe. It shows low-nanomolar potency in biochemical assays and modulates PRMT5-mediated arginine methylation in cellular models, supporting mechanistic studies of epigenetic regulation and PRMT5-dependent signaling. For research use only.

  • Potent PRMT5 inhibition at low-nanomolar concentrations.
  • High selectivity for PRMT5 versus related methyltransferases.
  • Cell-active modulation of arginine methylation in vitro.
  • Well-characterized for mechanistic and target validation studies.
  • Available in both free base and hydrochloride salt forms for formulation flexibility.

Catalog No. 50-002-15285


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