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Medchemexpress LLC Guadecitabine sodium | 929904-85-8 | C18H23N9NaO10P | 1 ML

Supplier: Medchemexpress LLC HY1522910MM/1ML
Guadecitabine sodium is a second-generation DNA methyltransferases (DNMT) inhibitor for research of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). It is for research use only and not sold to patients.
- Second-generation DNA methyltransferases (DNMT) inhibitor
- Induces dose-dependent increase in p16 expression
- Inhibits DNA methylation
- Effective in reducing DNA methylation and retarding tumor growth in vivo
- Reactivates p16 gene expression
- Better tolerated in vivo than 5-Aza-CdR
- Involved in numerous clinical trials for various conditions
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