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Medchemexpress LLC Guadecitabine sodium | 929904-85-8 | C18H23N9NaO10P | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1522950MG

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Guadecitabine sodium is a second-generation DNA methyltransferases (DNMT) inhibitor. It is used for research of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). This product is for research use only and not sold to patients.

  • Inhibits DNA methylation.
  • Increases p16 expression in HCT116 colorectal carcinoma and T24 cells.
  • Shows reduced toxicity compared to 5-aza-CdR at lower doses.
  • Reduces DNA methylation and retards tumor growth in vivo.
  • Exhibits improved tolerability in vivo compared to 5-Aza-CdR.

Catalog No. 50-003-73183


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