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Medchemexpress LLC HY-107738 5mg Medchemexpress, Guggulsterone CAS:95975-55-6 Purity:>98%
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Supplier:  Medchemexpress LLC HY1077385MG

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Medchemexpress, HY-107738 5mg Guggulsterone CAS:95975-55-6 Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products ( IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin ), modulation of cell cycle proteins ( cyclin D1 and c-Myc ), activation of caspases and JNK , inhibition of Akt [1] . Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC 50 s of 17 and 15 μM for Z- and E-Guggulsterone, respectively [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-193-2295


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