Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical GW 4869 hydrochloride hydrat
Supplier: Cayman Chemical 13127500 UG
An inhibitor of neutral sphingomyelinase (IC50 = 1 μM); selective for neutral sphingomyelinase over acid sphingomyelinase at concentrations up to 150 μM as well as B. cereus PC-PLC, human lyso-PAF PLC, and bovine PP2A at 10 μM; inhibits TNF-α-induced sphingomyelin hydrolysis and TNF-α-induced cell death in MCF-7 cells; reduces the inhibitory effects of OxPAPC and KOdiA-PE on LPS-induction of IL-8 in human aortic endothelial cells; reverses hypoxia-induced pulmonary vasoconstriction in rats at 1 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?